Important Safety Information About PRISTIQ
Suicidality and Antidepressant Drugs Antidepressants increased the risk of suicidal thinking and behavior in children, teens, and young adults. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy or when the dose is changed should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior such as becoming agitated, irritable, hostile, aggressive, impulsive, or restless. Should these occur, report them to a doctor right away. PRISTIQ is not approved for use in children under 18.

Do not take PRISTIQ if you are allergic to desvenlafaxine, venlafaxine, or any of the ingredients in PRISTIQ. Do not take PRISTIQ if you currently take, or have taken within the last 14 days, any medicine known as an MAOI (including intravenous methylene blue or the antibiotic linezolid).

Getting Results

Depression is a serious medical condition that can take so much out of you. But successfully treating depression is a realistic goal. So whether you’re new to treatment or you’ve tried treatments in the past, now is a good time to recommit to feeling better. PRISTIQ (desvenlafaxine) could be a key in treating your depression symptoms.
PRISTIQ is an effective treatment for depression in adults. It’s proven to treat the emotional and physical symptoms of depression as measured by the HAMD-17, a commonly used symptom rating scale. Some of these depression symptoms include:
Emotional Symptoms
  • Sadness
  • Irritability
  • Hopelessness
  • Feeling guilty
  • Loss of interest
    in activities
Physical Symptoms
  • Trouble sleeping
  • Agitation
  • Fatigue
  • Weight change
  • Difficulty
PRISTIQ 50 mg has been shown to help improve patients’ ability to function as measured by another scale, the SDS,* which includes:
  • Work
  • Social Life/Leisure Activities
  • Family Life/Home Responsibilities
How quickly does PRISTIQ work?

When taking PRISTIQ, it’s important to give it time to work. Everybody responds differently to treatment. In general, it can take several weeks to feel the full benefit of a prescription antidepressant, although some people will start to feel better sooner.

Don't stop taking PRISTIQ without first talking to your health care professional, even if you don't feel results right away.

Talk to your doctor about any concerns you may have.

How do I take PRISTIQ?

Most people start with a once-daily 50-mg dose of PRISTIQ (taken with or without food). Your doctor may keep you on your starting dose throughout your treatment. Talk to your doctor about any health conditions you may have, as your dose might be affected.

PRISTIQ should be taken at the same time each day and always swallowed whole, since the tablets are time released.

You should always take PRISTIQ exactly as instructed by your health care professional.

How can I track my progress on PRISTIQ?
Chart your progress while taking PRISTIQ with My Progress Tracker, an interactive tool that can help you keep track of how you’re feeling over time. Share your progress with your health care professional.
Can I stop taking PRISTIQ when I feel better?

Do not stop taking or change the dose of PRISTIQ without talking with your health care provider, even if you feel better. Stopping an antidepressant medicine suddenly can cause other symptoms.

Side effects may occur when stopping PRISTIQ (discontinuation symptoms), especially when therapy is stopped suddenly. Your health care provider may want to decrease your dose slowly to help avoid side effects. Some of these side effects may include:

  • Dizziness
  • Anxiety
  • Nausea
  • Abnormal dreams
  • Headache
  • Tiredness
  • Irritability
  • Sweating
  • Sleeping problems (insomnia)
  • Diarrhea

* vs. placebo as measured by Sheehan Disability Scale, a patient-rated measure of functional impairment.

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a health care provider. All decisions regarding patient care must be made with a health care provider, considering the unique characteristics of the patient.

The product information provided in this site is intended for residents of the United States. The products discussed herein may have different product labeling in different countries.

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