Important Safety Information About PRISTIQ
Suicidality and Antidepressant Drugs Antidepressants increased the risk of suicidal thinking and behavior in children, teens, and young adults. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy or when the dose is changed should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior such as becoming agitated, irritable, hostile, aggressive, impulsive, or restless. Should these occur, report them to a doctor right away. PRISTIQ is not approved for use in children under 18.

Do not take PRISTIQ if you are allergic to desvenlafaxine, venlafaxine, or any of the ingredients in PRISTIQ. Do not take PRISTIQ if you currently take, or have taken within the last 14 days, any medicine known as an MAOI (including intravenous methylene blue or the antibiotic linezolid).

Sign Up for Inside Depression Updates

Keep learning about depression with this free program that delivers insights and support directly to your inbox—with inspirational extras to help you stay focused on your commitment to feeling better.

Create a Doctor Discussion Guide

Create a list of customized questions about your condition that will help focus your conversation, so you can get the most out of your next doctor’s appointment.

Depression resources

The following are depression resources that we hope you find useful to help further educate yourself and your family and friends about this common and treatable disease.

The Web sites below are neither owned nor controlled by Pfizer. Pfizer does not endorse and is not responsible for the content or services of these sites.

  • American Psychiatric Foundation

    Committed to operating programs and funding initiatives that promote awareness of mental illnesses, the effectiveness of treatment, and the importance of early intervention.

  • Depression and Bipolar Support Alliance

    A patient-directed organization with a purpose of educating patients, families, and the public about the nature of depressive illness.


    Created by the American Psychiatric Association, the site provides information on psychiatric disorders such as depression and provides help locating a psychiatrist in your local area.

  • National Alliance on Mental Illness

    A support, educational, and advocacy organization for people with mental illness and their families, with over 1200 local affiliates; local affiliates give guidance to finding treatment.

  • National Institute of Mental Health

    The largest scientific organization in the world dedicated to research focused on the understanding, treatment, and prevention of mental disorders and the promotion of mental health.

  • Mental Health America (formerly, the National Mental Health Association)

    An association that works with over 340 affiliates to promote mental health through advocacy, education, research, and services.

  • Depression Connect

    An online community where you can ask questions, share experiences, and learn from other people whose lives are also touched by depression.

PRISTIQ®(desvenlafaxine) is a prescription medication approved for the treatment of major depressive disorder in adults. PRISTIQ is not indicated for the treatment of any other mental illness, including bipolar disorder or depressive episodes of bipolar disorder.

See How PRISTIQ Can Help >

PRISTIQ could be a key in treating your depression symptoms.

Browse Other Articles

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a health care provider. All decisions regarding patient care must be made with a health care provider, considering the unique characteristics of the patient.

The product information provided in this site is intended for residents of the United States. The products discussed herein may have different product labeling in different countries.

Copyright © 2013 Pfizer Inc. All rights reserved. PQP580408-01