Impact of Depression

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The impact of depression

f you’re among the 121 million people worldwide with depression, you certainly know how it impacts you, both physically and emotionally. What you may not know is, society pays a price that reaches well beyond the symptoms of the condition.

Here are some ways depression has become a growing global concern:

Depression is among the leading causes of medical disability worldwide.
80% of depressed people reported being impaired in their daily functioning, with 27% reporting serious difficulties in work and home life.
35% of males and 22% of females with depression reported that their depressive symptoms made it very or extremely difficult for them to work, get things done at home, or get along with other people.
When experiencing a depressive episode, people lose 5.6 hours of productive work every week.
People with depression are 6 times more likely to be unemployed.

The impact of depression

What’s depression costing you?

The societal cost of depression is high, but the cost in human suffering cannot be estimated. Depression can take so much out of you. It can make you feel sad, helpless, and uninterested in your favorite activities. Sometimes depression can make you feel like you have to wind yourself up to get through the day.

Depression is a real medical condition that can’t be willed or wished away. People with depression cannot merely "pull themselves together" and get better. Understanding depression may help you start to realize that it is not a personal weakness.

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Important Safety Information About PRISTIQ

Suicidality and Antidepressant Drugs Antidepressants increased the risk of suicidal thinking and behavior in children, teens, and young adults. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy or when the dose is changed should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior such as becoming agitated, irritable, hostile, aggressive, impulsive, or restless. Should these occur, report them to a doctor right away. PRISTIQ is not approved for use in children under 18.

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Important Safety Information About PRISTIQ

Suicidality and Antidepressant Drugs

Antidepressants increased the risk of suicidal thinking and behavior in children, teens, and young adults. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy or when the dose is changed should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior such as becoming agitated, irritable, hostile, aggressive, impulsive, or restless. Should these occur, report them to a doctor right away. PRISTIQ is not approved for use in children under 18.

Do not take PRISTIQ if you are allergic to desvenlafaxine, venlafaxine, or any of the ingredients in PRISTIQ. Do not take PRISTIQ if you currently take, or have taken within the last 14 days, any medicine known as an MAOI (including intravenous methylene blue or the antibiotic linezolid). Allow 7 days after stopping PRISTIQ before starting an MAOI. Taking an MAOI with PRISTIQ can cause serious or even life-threatening side effects.

Before taking PRISTIQ, tell your healthcare professional about all prescription and over-the-counter medications and supplements you take or plan to take including: those to treat migraines or psychiatric disorders (including other antidepressants) to avoid serotonin syndrome, a potentially life-threatening condition; aspirin, NSAID pain relievers, or blood thinners because they may increase the risk of bleeding.

PRISTIQ may cause or worsen some conditions, so tell your healthcare professional about all the medical conditions you have or had including:

High blood pressure, which should be controlled before starting PRISTIQ and monitored regularly
Heart problems, high cholesterol or triglyceride levels, a history of stroke, glaucoma or increased eye pressure, kidney or liver problems, or low sodium levels in your blood
Bleeding problems
Depression, suicidal thoughts or behavior
Mania, bipolar disorder, or seizures or convulsions
Nursing, pregnancy, or plans to become pregnant

Discontinuation symptoms may occur when stopping or reducing PRISTIQ, so talk to your healthcare professional before stopping or changing your dose.

Until you see how PRISTIQ affects you, be careful driving a car or operating machinery. Avoid drinking alcohol while taking PRISTIQ.

In clinical studies, most common side effects with PRISTIQ 50 mg were nausea, dizziness, sweating, constipation, and decreased appetite.

INDICATION

PRISTIQ^® (desvenlafaxine) is a prescription medication approved for the treatment of major depressive disorder in adults.

Please see full Prescribing Information, including boxed warning, and Medication Guide.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a health care provider. All decisions regarding patient care must be made with a health care provider, considering the unique characteristics of the patient.

The product information provided in this site is intended for residents of the United States. The products discussed herein may have different product labeling in different countries.

Important Safety Information | Medication Guide for Patients | Prescribing Information |

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