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PRISTIQ supports
you throughout your
treatment with My
Progress Tracker. This
downloadable interactive tool lets you easily chart your progress over time, and share your results with your doctor. See demo

Get up to $15* off your
out-of-pocket cost on every prescription. Find Out How *Terms and Conditions apply.

Keeping Your Doctor Informed

Put all the medicines you're taking in a bag and bring them with you to your doctor's appointment. That way, you won't forget to tell your doctor what you’re taking.

Before taking PRISTIQ, discuss the information below with your health care professional.

Your medical conditions

Tell your doctor about all medical conditions, especially if you have (or have had):

  • high blood pressure
  • heart problems
  • high cholesterol or high triglycerides
  • a history of stroke
  • glaucoma
  • kidney problems
  • liver problems
  • seizures or convulsions
  • mania or bipolar disorder
  • low sodium levels in your blood

Note: Your health care professional should check your blood pressure regularly while you are taking PRISTIQ.

If you are nursing, pregnant, or plan to become pregnant

Tell your doctor, as it is not known if taking PRISTIQ will harm your unborn baby.

Prescription and over-the-counter medications

Tell your doctor about all medicines you are taking or plan to take, including:

  • Medicines to treat migraines or psychiatric disorders. Taken with PRISTIQ, they may cause a potentially life-threatening condition.
  • Aspirin, NSAID pain relievers, or blood thinners. Taken with PRISTIQ, they may increase the risk of bleeding.
  • Medicines used to treat mood, anxiety, psychotic, or thought disorders, including tricyclics, lithium, selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), antipsychotic drugs, or other dopamine antagonists, such as metoclopramide
  • Silbutramine
  • Tramadol
  • St. John’s Wort
  • MAOIs (including linezolid, an antibiotic)
  • Tryptophan supplements

Keep a list of all medications you have taken or plan to take to show your health care professional. Do not start new medications without first checking with your health care professional.

Stopping your medication

Stopping an antidepressant medicine, especially suddenly, can cause side effects called discontinuation symptoms. Your health care professional may want to gradually reduce your dose slowly to help avoid these side effects. Therefore, do not stop taking or change the dose of PRISTIQ without first talking to your health care professional, even if you feel better. Only your health care professional can tell you how long you should use PRISTIQ.

Next: Side Effects »

Indication

PRISTIQ® is approved for the treatment of major depressive disorder in adults.

Important Safety Information for PRISTIQ

Suicidality and Antidepressant Drugs

Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, teens, and young adults. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. PRISTIQ is not approved for use in children under 18.

  • People taking MAOIs should not take PRISTIQ.
  • All patients taking antidepressants should be observed closely for signs that their condition is getting worse or that they are becoming suicidal. This is very important when an antidepressant is started or when the dose is changed. Patients should be watched for becoming agitated, irritable, hostile, aggressive, impulsive, or restless. These symptoms should be reported to the patient's health care professional right away.
  • Tell your health care professional about all prescription and over-the-counter medications you are taking or plan to take, including:
    • Medicines to treat migraines or mood disorders, to avoid a potentially life-threatening condition
    • Aspirin, NSAID pain relievers, or blood thinners, because they may increase the risk of bleeding.
  • PRISTIQ may cause or make some conditions worse, so tell your health care professional about all your medical conditions, including if you:
    • Have high blood pressure. Your blood pressure should be controlled before you start taking PRISTIQ and monitored regularly
    • Have heart problems, high cholesterol or triglyceride levels, or a history of stroke
    • Have glaucoma or increased eye pressure
    • Have kidney or liver problems
    • Have or had bleeding problems
    • Have or had depression, suicidal thoughts or behavior
    • Have or had mania, bipolar disorder, or seizures or convulsions
    • Have low sodium levels in your blood
    • Are nursing, pregnant, or plan to become pregnant.
  • Discontinuation symptoms may occur when stopping PRISTIQ, especially when therapy is stopped suddenly. Talk to your health care professional before you stop taking or reduce the dose of PRISTIQ.
  • Until you see how PRISTIQ affects you, be careful driving a car or operating machinery. Avoid drinking alcohol while taking PRISTIQ.
  • Side effects when taking PRISTIQ 50 mg may include nausea, dizziness, sweating, constipation, and decreased appetite.

Please see full Prescribing Information including boxed warning and Medication Guide.



Uninsured? Need help paying for Pfizer medicines? Pfizer has programs that can help.
Call 1-866-706-2400 or click here www.PfizerHelpfulAnswers.com
*Save up to $15 a month, up to $180 in savings per year. Terms and Conditions apply. The PRISTIQ Savings Card is not health insurance. The card will be accepted only at participating pharmacies. No membership fees. For more information about the PRISTIQ Savings Card, please call 1-800-842-6031 or write to:
PRISTIQ Savings Card
Pfizer Inc.
235 East 42nd Street
NY, NY 10017