Antidepressants increased the risk of suicidal thinking and behavior in children,
teens, and young adults. Depression and certain other psychiatric disorders are
themselves associated with increases in the risk of suicide. Patients of all ages
who are started on antidepressant therapy or when the dose is changed should be
monitored appropriately and observed closely for clinical worsening, suicidality,
or unusual changes in behavior such as becoming agitated, irritable, hostile, aggressive,
impulsive, or restless. Should these occur, report them to a doctor right away.
PRISTIQ is not approved for use in children under 18.
Do not take PRISTIQ if you are allergic to desvenlafaxine, venlafaxine, or any of
the ingredients in PRISTIQ. Do not take PRISTIQ if you currently take, or have taken
within the last 14 days, any medicine known as an MAOI (including intravenous methylene
blue or the antibiotic linezolid). Allow 7 days after stopping PRISTIQ before starting
an MAOI. Taking an MAOI with PRISTIQ can cause serious or even life-threatening
Before taking PRISTIQ, tell your healthcare professional about all prescription
and over-the-counter medications and supplements you take or plan to take including:
those to treat migraines or psychiatric disorders (including other antidepressants)
to avoid serotonin syndrome, a potentially life-threatening condition; aspirin,
NSAID pain relievers, or blood thinners because they may increase the risk of bleeding.
PRISTIQ may cause or worsen some conditions, so tell your healthcare professional about all
the medical conditions you have or had including:
High blood pressure, which should be controlled before starting PRISTIQ
and monitored regularly
Heart problems, high cholesterol or triglyceride levels, a history of stroke, glaucoma
or increased eye pressure, kidney or liver problems, or low sodium levels in your
Depression, suicidal thoughts or behavior
Mania, bipolar disorder, or seizures or convulsions
Nursing, pregnancy, or plans to become pregnant
Discontinuation symptoms may occur when stopping or reducing PRISTIQ, so talk to your healthcare
professional before stopping or changing your dose.
Until you see how PRISTIQ affects you, be careful driving a car or operating machinery. Avoid drinking
alcohol while taking PRISTIQ.
In clinical studies, most common side effects with PRISTIQ 50 mg were nausea, dizziness, sweating, constipation, and decreased appetite.
(desvenlafaxine) is a prescription medication approved for the treatment of major depressive disorder in adults.
You are encouraged to report negative side effects of prescription drugs to the
FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
The health information contained herein is provided for educational purposes only
and is not intended to replace discussions with a health care provider. All decisions
regarding patient care must be made with a health care provider, considering the
unique characteristics of the patient.
The product information provided in this site is intended for residents of the United
States. The products discussed herein may have different product labeling in different